Ophthalmology Outcomes
Pediatric and Adult Strabismus Surgery
Ophthalmologists with joint appointments at Boston Children’s Hospital and the Mass Eye and Ear Pediatric Ophthalmology and Strabismus Service offer subspecialized medical and surgical care for the full spectrum of pediatric ophthalmic disorders, including strabismus (in children and adults), cataract, anterior segment disease, oculoplastic surgery, neuro-ophthalmology, ocular trauma, ocular oncology, inherited retinal degenerations, and vitreoretinal surgery.
Pediatric and Adult Strabismus Surgery
Strabismus surgery is the most commonly performed ophthalmic procedure in children. This type of surgery is also performed on adults with new or previously existing ocular misalignment. Recession and resection procedures are typically performed for horizontal misalignment (esotropia and exotropia); other approaches include tuck, loop myopexy and transposition procedures for horizontal, vertical and torsional forms of misalignment. Adjustable sutures are used routinely in children and adults. The service has a high rate of quaternary referrals from other pediatric and strabismus specialists to manage the rarest and most complex cases, with nearly half of all patients treated having undergone prior strabismus surgery.
Distribution of Strabismus Patients by Age and Surgical Approach
The Strabismus Service at Boston Children’s Hospital offers comprehensive evaluation and treatment for children and adults with strabismus. In 2023, 807 total strabismus procedures were performed at Boston Children’s Hospital, Massachusetts Eye and Ear, the University of Massachusetts, and other Harvard affiliates. These procedures addressed misalignments that were horizontal, vertical, and torsional in nature.
Distribution of Risk Factors in Strabismus Patients
Of the 807 total strabismus surgeries performed in 2023, 393 patients presented with risk factors associated with a worse surgical outcome. Of these 393 patients with risk factors, the most common risk factors were a history of prior strabismus surgery (46.6%), divergence insufficiency (8.4%), and 4th nerve palsy (7.1%). Other common risk factors were 6th nerve palsy, cerebral palsy, Duane syndrome, heavy eye syndrome, 3rd nerve palsy, developmental delays, premature birth, craniofacial disorders, high myopia, brain tumor, Down Syndrome, and nystagmus.
Goal-Determined Outcomes
Since the desired surgical outcome depends on the primary indication for surgery, we used a goal-determined methodology to assess outcomes of horizontal strabismus surgery.1,2 The reported outcomes include procedures performed by ophthalmologists with joint appointments at Boston Children’s Hospital and the Mass Eye and Ear Pediatric Ophthalmology and Strabismus Service. Procedures performed by the Mass Eye and Ear Adult Neuro-Ophthalmology service are not included in this analysis.
Before and After Horizontal Strabismus Surgery

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Goal-Deterined Outcomes
1. Ehrenberg M, Nihalani BR, Melvin P, Cain CE, Hunter DG, Dagi LR. Goal-determined metrics to assess outcomes of esotropia surgery. J AAPOS 2014; 18(3): 211-216.
2. Chang YH, Melvin P, Dagi LR. Goal-determined metrics to assess outcomes of exotropia surgery. J AAPOS 2015; 19: 304-310.
Exotropia Outcomes Stratified by Risk Factors
1. Chang YH, Melvin P, Dagi LR. Goal-determined metrics to assess outcomes of exotropia surgery. J AAPOS 2015; 19: 304-310.
Esotropia Outcomes Stratified by Risk Factors
1. Ehrenberg M, Nihalani BR, Melvin P, Cain CE, Hunter DG, Dagi LR. Goal-determined metrics to assess outcomes of esotropia surgery. J AAPOS 2014; 18(3): 211-216.
Scleral Perforation During Strabismus Surgery
1. Bradbury JA. What information can we give to the patient about the risks of strabismus surgery. Eye (Lond) 2015; 29(2): 252-257.
2. Awad AH, Mullaney PB, AI-Hazmi A, et al. Recognized globe perforation during strabismus surgery: incidence, risk factors, and sequelae. J AAPOS 2000; 4(3): 150-153.
3. Morris RJ, Rosen PH, Fells P. Incidence of inadvertent globe perforation during strabismus surgery. Br J Ophthalmol 1990; 74(8): 490-493.
Infection Within 30 Days After Surgery
1. Ing MR. Infection following strabismus surgery. J Ophthalmic Nurs Technol 1991; 10(5): 211-214.
2. Bradbury JA. What information can we give to the patient about the risk of strabismus surgery. Eye (Lond) 2015; 29(2): 252-257.
3. Brenner C, Ashwin M, Smith D, et al. Sub-Tenon's space abscess after strabismus surgery. J AAPOS 2009; 13(2): 198-199.
4. Bradbury JA, Taylor RH. Severe complications of strabismus surgery. J AAPOS 2013; 17(1): 59-63.
5. Haripriya A, Chang DF, Reena M, et al. Complication rates of phacoemulsification and manual small-incision cataract surgery at Aravind Eye Hospital. J Cataract Refract Surg. 2012; 38(8): 1360-1369.
6. Sharma N, Pushker N, Dada T, et al. Complications of pediatric cataract surgery and intraocular lens implantation. J Cataract Refract Surg.1999; 25(12): 1585-1588.
7. Pandey SK, Wilson ME, Trivedi RH, et al. Pediatric cataract surgery and intraocular lens implantation: current techniques, complications, and management. Int Ophthalmol Clin 2001; 41(3): 175-196.
8. Lee EW, Holtebeck AC, Harrison AR. Infection rates in outpatient eyelid surgery. Ophthal Plast Reconstr Surg 2009; 25(2): 109-110.
